Place a red blood cell in a neutral or high concentration solution. Concentrate the salts inside the cell or shrink it as a result of water loss

Place a red blood cell in a neutral solution Concentration:
Water does not move and the cell remains in normal size because the concentration of extracellular salts equals the concentration of salts within the cell.

Place a red blood cell in a high concentration solution:
Water moves from within the less concentrated saline to the higher concentration of the salts, leading to shrinkage of the cell due to loss of water.