In 2001 , Which analgesic experienced significant misuses and diversion, requiring revisions in the warning section of the product labeling

In 2001 , Which analgesic experienced significant misuses and diversion, requiring revisions in the warning section of the product labeling?
A. Oxy contin
B. Demerol
C. Tylenol #3
D. Toradol
E. roxanol.